Active

.406 Ventures

Investor type

VC

Founded

2005

AUM

$1 400 M

Location

Boston, Massachusetts, United States

Investment Ticket

$0-1 m

Investment Stage

Seed Series A

Region of investment

North America Europe
Investor profile last updated: 11 April, 2025

Profile

We love being involved in the first institutional capital round (typically the Series A)—early enough to be able to truly partner with you and materially impact the growth trajectory of your company.

Your company matters.
We limit the number of investments in each portfolio to ensure adequate capital and partner bandwidth per company to maximize the chances of success across the board. With .406, you do not get one or two partners, you get the resources of our full team—every investment team member touches every company. We are also dogmatic about never investing in competitive companies, so we will be explicitly aligned with you.

Operational experience and entrepreneurial roots are at .406’s core.
We may not have seen and done it all, but we certainly know what it is like to build an entrepreneurial company. Our years of experience starting and running our own businesses give us personal insight and access to deep networks that we can offer you as you work to build a great company.

We are nimble, flexible and wear many hats for our entrepreneurs.
And while we apply our skills and lessons learned across our portfolio, we realize that your company has unique needs and requires a customized approach.

We invest in companies aiming to disrupt industries that we know extremely well
and where we have the networks to truly accelerate company success.

Extraordinary People
We invest in entrepreneurs and teams who have demonstrated a passion to achieve the impossible, usually in impossibly little time and on ridiculously limited resources.

Large Markets
There are great ideas and there are good market opportunities; we look for both. We also believe that venture capital is not the right form of capital for every situation, so we will help you make sure that we have an aligned fit and plan for success.

Unique Technology
We invest in technologies and tech-driven services that solve thorny problems for big markets in unique and compelling ways. Applying these criteria, we focus on:

Cybersecurity

Digital Health

Data and Cloud

Industry

Digital Fashion/Beauty Financial Services Fintech Healthcare Services Marketing and Advertising Media and Entertainment Other Real Estate Security Software Sports/SportsTech Telecommunications Energy Cloud Cybersecurity HealthTech MedTech AI Business Services (B2B) Technology SaaS CleanTech

.406 Ventures Funds

Name Type
Questionare
Industry
Questionare
Stage
Questionare
Region
Size AUM Launch date
.406 Ventures Fund V
Venture Capital (VC)
Healthcare Services
AI
Cybersecurity
Seed
Series A
North America
$1-5 m
$265 M
October 2024
.406 Ventures Fund III
Venture Capital (VC)
Business Services (B2B)
Fintech
Healthcare Services
AI
Technology
Cybersecurity
Series A
North America
$5-10 m
$217 M
July 2015
.406 Ventures Fund II
Venture Capital (VC)
AI
Technology
Pre-seed
Seed
North America
$5-10 m
$175 M
December 2012
.406 Ventures Fund IV
Venture Capital (VC)
Software
AI
Technology
Cybersecurity
HealthTech
Pre-seed
Seed
North America
$5-10 m
$294 M
December 2019
.406 Ventures 2016 Opportunities Fund, L.P.
Venture Capital (VC)
Financial Services
Fintech
Healthcare Services
Marketing and Advertising
Media and Entertainment
SaaS
Security
Software
Energy
CleanTech
HealthTech
Pre-seed
Seed
North America
Europe
Middle East
$5-10 m
$80 M
December 2016
.406 Ventures 2016 Opportunities Fund II
Venture Capital (VC)
Financial Services
Fintech
Healthcare Services
Marketing and Advertising
Media and Entertainment
SaaS
Security
Software
Energy
CleanTech
HealthTech
Pre-seed
Seed
North America
$5-10 m
—
December 2019

Contacts

Name
Title
Email
avatar
Graham Brooks Partner
Partner
g•••@•••
avatar
Liam Donohue Founding Partner
Founding Partner
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FAQs about .406 Ventures

.406 Ventures is a venture capital firm. It backs companies at Seed and Series A, writing tickets of $0-1 m.
.406 Ventures is located in Boston, Massachusetts, United States.
.406 Ventures was founded in 2005.
.406 Ventures invests in companies and startups in Digital, Fashion/Beauty, Financial Services, Fintech, Healthcare Services, Marketing and Advertising, Media and Entertainment, Other, Real Estate, Security, Software, Sports/SportsTech, Telecommunications, Energy, Cloud, Cybersecurity, HealthTech, MedTech, AI, Business Services (B2B), Technology, SaaS, CleanTech.
.406 Ventures invests in companies and startups in North America, Europe.
.406 Ventures invests in companies and startups at Seed, Series A.
.406 Ventures usually invests $0-1 m on average.
.406 Ventures has around $1 400m assets under management.
.406 Ventures last fund was created/launched in 2024-10-14
.406 Ventures can be reached through its website 406ventures.com, its LinkedIn page and its X account. Its general enquiries address is contact@406ventures.com. Cold-mailing a general inbox rarely reaches a partner, so Private Equity List also lists the investment-team contacts for .406 Ventures — names, roles, verified work emails and LinkedIn profiles — available on a Pro plan from $129/month (see pricing). Contacts are sourced from the firm's website and LinkedIn and re-verified on a rolling cycle. Spot a stale contact, or none at all? Report it — we re-run that firm within 48h and get back to you.
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Private Equity List re-verifies investor profiles on a rolling cycle, pulling from the firm's own website and LinkedIn rather than a one-off import. This profile was last updated on 11 April, 2025. Something out of date here? Report it — we re-run that firm within 48h and get back to you.